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Continuous monitoring of regional cerebral blood flow: experi-mental and clinical validation of a novel thermal diffusion microprobe. As long ago as 1985, a ‘permissivehypercapnia’ strategy was advocated by Wung inventilation of infants with PPHN, well before itwas introduced into adult medicine (Wung et al.1985)

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[ 121] studied the DNA methylation status of both P1and P2 promoters as a means of epigenetic transcriptional control of their corre-sponding isoforms in 102 primary NSCLCs and reported that the P2 hypomethylation-associated overexpression of ??p73 mRNA is a frequent event, particularly amongsquamous cell carcinomas.

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Diffuse axonal pathology detected with magnetization transfer imaging follow-ing brain injury in the pig. Resorption ofthyroglobulin at this stage can be confirmed by thepresence of large endocytic vesicles called colloidalresorption droplets in the apical region ofthe follic-ular cells. Effect of digitalistreatment on survival after acute myocardial infarction. Inflammation and destruction of intervertebral disk is visible (arrow). Of course, much work remains to clarify (orfalsify) such intriguing hypotheses, yet the importance ofthe common clinical comorbidity of pain and depressioncannot be denied, however incompletely we may under-stand their intersection.

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Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M et al (1993) Gain of functionmutations in p53.

Withthe exception of metabolism parameters, fetal parameterswere scaled in a similar manner to the maternal parame-ters; PAs were scaled by v 0.75, where v is the volume ofthe fetus, and then multiplied by the total number of fetusesto obtain the value for the litter. Neurologic disor-ders commonly increase in incidence with age.
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